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Several studies have been conducted to test the efficacy
of acupuncture in treating a variety of disorders. Acupuncture can effectively
relieve many symptoms with minimal adverse effects.
Shen
J, et al. Electroacupunture for control of myeloablative chemotherapy-induced
emesis. A randomized controlled trial. JAMA
2000;284(21):2755-2761.
In this study, 104 breast cancer patients undergoing chemotherapy were
randomly assigned to receive electroacupuncture at antiemetic acupuncture
points once daily for 5 days; minimal needling at control points with mock
stimulation once daily for 5 days; or antiemetic drugs alone. All the patients
received the same chemotherapeutic and antiemetic drugs. At the end of 5 days,
patients who received electroacupuncture reported fewer episodes of vomiting
compared to those who received minimal needling or antiemetic drugs alone.
However, these effects were not observed at a follow-up done from days 6-14.
Researchers concluded that electroacupuncture was effective in short-term in
controlling emesis associated with chemotherapeutic treatment in breast cancer
patients.
Alimi
D, et al. Analgesic effect of auricular acupuncture for cancer pain: A
randomized, blinded, controlled trial. J Clin Oncol
2003;21(22):4120-4126.
Ninety cancer patients were randomly assigned to receive two courses
of true auricular acupuncture; auricular acupuncture at placebo points; or
with auricular seeds fixed at placebo points. At a 2-month assessment,
patients who received acupuncture reported a 36% decrease in pain from
baseline compared to 2% in those who received placebo. Researchers concluded
that acupuncture significantly reduced pain in cancer patients, despite being
treated with analgesics.
Vickers
AJ, et al. Acupuncture for postchemotherapy fatigue: A phase II study. J
Clin Oncol 2004;22(9):1731-1735.
This study involved cancer patients who had completed chemotherapy but
experienced persistent fatigue. 25 patients received acupuncture twice a week
for 4 weeks and 12 patients received acupuncture once a week for 6 weeks.
Patients reported an improvement of 31% in fatigue level measured at 2 weeks
after the final treatment compared to the baseline. There was no significant
difference in weekly and bi-weekly treatments. The result suggests that
acupuncture has benefit in treating postchemotherapy fatigue. However, this is
only a preliminary study on a small number of patients and was not randomized.
Further studies involving large number of patients are warranted.
Vickers
AJ, et al. Acupuncture for chronic headache in primary care: large, pragmatic,
randomized trial. BMJ 2004;328(7442):744-49.
In this study, 401 patients with chronic headache were randomly assigned to
receive up to 12 acupuncture treatments over a period of 3 months or
conventional treatment. Patients in the acupuncture group reported fewer
headaches, less use of medication, fewer visits to doctors, and improved
quality of life compared to those who received conventional care. Researchers
concluded that acupuncture offers persistent clinical benefits for patients
with chronic headache, particularly migraine.
Xue
CCL, et al. Electroacupuncture for tension-type headache on distal acupoints
only: A randomized, controlled, crossover trial. Headache
2004:44:333-41.
In this study, 37 patients with tension-type headache were randomly
assigned to receive real electroacupuncture or sham electroacupuncture for 4
weeks. Following a washout period of 2 weeks, the order of the treatments was
reversed. Patients who initially received real treatment were switched to
placebo and those who received placebo were given real acupuncture for 4 more
weeks. Patients who received real acupuncture reported significant improvement
in frequency of headaches, the duration of headaches, and intensity of pain
compared to the placebo treatment. However, the effect was not observed at a
3-month follow-up.
Ng
DK, et al. A double-blind, randomized, placebo-controlled trial of acupuncture
for the treatment of childhood persistent allergic rhinitis. Pediatrics
2004;114(5):1242-1247.
Seventy-two children in Hong Kong, ages 6-20, with persistent allergic
rhinitis were randomly assigned to active and sham acupuncture groups.
Patients in the active group received acupuncture at three different acupoints
with 1.2 ?2.4 cm needle penetration whereas those in the sham group
received acupuncture at the same acupoints but to a depth of only 0.3 cm. The
treatment consisted of 2 sessions of acupuncture every week for 8 weeks for
both the groups. Following treatment, those in the active group had reduced
symptoms of rhinitis and increased in symptom-free days. But there was no
difference in use of daily relief medication, serum IgE levels, or nasal
eosinophil counts. The effects of acupuncture were also short-term, lasting
for 10 weeks. More studies are needed to address the frequency, intensity, and
duration of acupuncture treatments and should include children from different
cultural backgrounds to rule out any bias.
Broide
E, et al. Effectiveness of Acupuncture for treatment of childhood
constipation. Dig Dis Sci 2001;46(6):1270-1275.
This study included 17 children, ages 3-13, constipated
for at least six months. The treatment consisted of five weekly
placebo acupuncture sessions, followed by 10 weekly true acupuncture sessions.
The needles were inserted into the stratum corneum and in regions located near
true acupuncture points for the placebo treatment. The actual treatment
consisted of subdermal insertion of the needles at true acupunture points. The
frequency of bowel movements improved after five sessions of true acupuncture.
Researchers suggest that acucpuncture may be used as an alternative option to
treat chronic constipation in children. However, since the study was designed
to administer both the placebo and actual treatments to the same patient, the
effectiveness of acupuncture in treating constipation is not clear as it is
possible that part of the problem may have resolved during the placebo
sessions. Further studies involving more patients and proper controls are
warranted.
REFERENCES
(1) Vickers AJ, et al. Acupuncture
for postchemotherapy fatigue: a phase II study. J Clin Oncol
2004;22(9):1731-35.
(2) Vickers AJ, et al. Acupuncture
for chronic headache in primary care: large, pragmatic, randomized trial. BMJ
2004;328(7442):744.
(3) Xue CCL, et al. Electroacupuncture
for tension-type headache on distal acupoints only: A randomized, controlled,
crossover trial. Headache 2004;44(4):333-41.
(4) Gan TJ, et al. A
randomized controlled comparison of electro-acupoint stimulation or
ondansetron versus placebo for the prevention of postoperative nausea and
vomiting. AnesthAnal 2004;99(4):1070-75.
(5) Alimi D, et al. Analgesic
effect of auricular acupuncture for cancer pain: A randomized, blinded,
controlled trial. J Clin Oncol 2003;21(22):4120-26.
(6) Shen J, et al.Electroacupuncture
for control of myeloablative chemotherapy-induced emesis: A randomized,
controlled trial. JAMA 2000;284(21):2755-61.
(7) Johnstone PA, et al. Acupuncture
for xerostomia: clinical update. Cancer 2002;94(4):1151-56.
(8) Pomeranz B and Chiu D. Naloxone
blockade of acupuncture analgesia: endorphin implicated. Life Sci
1976;19(11):1757-62.
(9) Pomeranz B and Warma N. Electroacupuncture
suppression of a nociceptive reflex is potentiated by two repeated
electroacupuncture treatments: the first opioid effect potentiates a second
non-opioid effect. Brain Res 1988;452(1-2):232-36.
(10) Peets JM and Pomeranz B. CXBK
mice deficient in opiate receptors show poor electroacupuncture analgesia. Nature
1978;273(5664):675-76.
(11) Baldry PE. Acupuncture, trigger points and musculoskeletal pain, 2nd
ed. London: Churchill Livingstone; 1993
(12) Yoo SS, et al. Modulation
of cerebellar activities by acupuncture stimulation: evidence from fMRI study.
Neuroimage 2004;22(2):932-40.
(13) Shin YH, et al. Effect
of acupressure on nausea and vomiting during chemotherapy cycle for Korean
postoperative stomach cancer patients. Cancer Nurs. 2004
Jul-Aug;27(4):267-74.
(14) Ng DK, et al. A
double-blind, randomized, placebo-controlled trial of acupuncture for the
treatment of childhood persistent allergic rhinitis. Pediatrics
2004;114(5):1242-1247.
(15) Broide E, et al. Effectiveness
of Acupuncture for treatment of childhood constipation. Dig Dis Sci
2001;46(6):1270-1275.
| Written:
| 10/01/2004 |
| Updated: |
12/06/2004 |